Bioperine or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Dicaffeine Malate is actually a combination of caffeine and malic acid. Malic acid in turn is won out of Apple Juice and is a food additive with the E number E296. In green apples, the sour taste is due to malic acid. When cocaine was outlawed, The Coca-Cola Company introduced dicaffeine malate as the replacement. It is a stimulant, much like caffeine, but apparently gentler on the digestive tract. Many traits associated with regular caffeine are found in this caffeine salt, but through the interaction with malic acid, additional features have been observed. Dicaffeine malate is a very common ingredient in dietary supplements, it is supposed to optimize energy levels, increase mental focus and cognitive awareness, but also is able to stimulate thermogenesis.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Forslean is extracted from the roots of the Coleus forskohlii. It is a popular ingredient in many weight loss and bodybuilding supplements because recent research shows it to initiate a chemical process in the body that results in burning of energy and fat cells. Forslean is shown to increase thyroid activity, which increases metabolism. Increase in metabolism results in burning of more calories, thus helping users lose weight. Some research also claims that Forslean can increase muscle gains in body builders while burning fat at the same time. It is also claimed to cure mood disorders.

Fucoxanthin is a component found in green sea weed that is avidly utilized in promoting excessive weight loss in individuals.

Guggulsterone is a plant sterol found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor, which was earlier believed to result in decreased cholesterol synthesis in the liver.

Razberi-K is a ketone unique to raspberry. Raspberry is rich in bioactive elements that are good for health. It is beneficial in reducing fats in the body. It helps decrease fat levels in the body in two ways: by reducing absorption of dietary fat and; by enhancing liplysis induced by norepinephrine. Research has found that increasing lipolysis can help boost glycerol release, enhancing translocation of hormone sensitive lipase in fat cells. Due to its fat burning ability, it is beneficial in weight reduction. It also has the capability of enhancing metabolic efficiency and decreasing production of harmful free radicals in the body.

Sclareolide is a terpenoid, commonly won out of salvia sclarea, also called clary sage, which is a biennial herb. It grows predominantly in Europe and in Asia, but is most common in Syria, Italy, Switzerland and France. Sclareolide stimulates adenylite cyclase, which is an enzyme increasing cyclic adenosine monophosphate levels in the body. It actually increases your metabolism rate and turns energy into heat. The overall effect is that you burn more calories, whereby further energy is provided by extraction of fat from their storage spaces. The increased lipolysis leads to removal of excess fat, but also to much leaner physique and better muscle definition. Sclareolide may in excess dosages lead to vasodilatory effects, increasing thereby the blood pressure. Slight antidepressant action may also occur.